Úvod - Diagnostika a léčba - Antiseizure Medication Therapy - Medication Withdrawal

Medication Withdrawal

In patients who have been seizure-free for several years, discontinuation of anti-seizure medication may be considered, but only after careful evaluation of all potential risks. Any decision to stop treatment should be made in close consultation with a neurologist, taking into account the type of epilepsy, patient history, and risk of seizure recurrence.

Discontinuation of anti-seizure medication in epilepsy patients can be considered only after a seizure-free period of at least 2–3 years. The decision takes into account not only the EEG findings, but more importantly, the type of epilepsy and the patient’s informed preference.

Medication withdrawal is a gradual and carefully managed process. Tapering typically starts with the ASM (anti-seizure medication) given in the lowest dose, while the medication presumed to have the greatest therapeutic effect is reduced last.

During the tapering period, patients should be especially diligent in following lifestyle recommendations, and those close to them—family, partners, or caregivers—should be informed about the process.

The risk of seizure recurrence after withdrawal is approximately 25–50%. A single breakthrough seizure can have serious consequences for people who were previously well-controlled—impacting employment, driving eligibility, and family responsibilities.

For this reason, many patients opt to continue treatment, particularly if they are taking modern ASM that are well tolerated and have minimal side effects.

Rescue Medication

Medications Restricted to Use in Centers of Highly Specialized Care

Medication Withdrawal

Need to schedule a follow-up appointment or running out of medication?

Need to schedule a follow-up appointment or running out of medication?